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There is no definitive evidence that B12 is better absorbed at a specific time of day

Thus, B12, what gives

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Those attaining the highest blood levels of vitamin D did lose more weight than other women, but this may not have been due to vitamin D

You can also learn more about vitamin B12, weight loss, and wellness by exploring the ThinWorks blog and client resources. Final Takeaway: The Best Time to Take Vitamin B12 For most people, the best time to take vitamin B12 is in the morning or early afternoon, ideally on an empty stomach with a glass of water, so it can support daytime energy and avoid potential sleep disruption

Vitamin B-6 is involved in nearly 60 enzyme systems in the body