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TB-500 is a synthetic fragment of Thymosin Beta-4 whose core proposed action is the sequestering of G-actin to regulate actin polymerization the process behind cell migration in wound healing and which has been linked preclinically to angiogenesis and reduced inflammation [3] [4]
Frequency: one subcutaneous injection each day , typically in the evening before bedtime, titrating up gradually as tolerated [5] [6]
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B12 absorption declines with age (4)
It is also used to treat pernicious anemia, vitamin B 12 deficiency (due to low intake from food or inability to absorb due to genetic or other factors), thyrotoxicosis, hemorrhage, malignancy, liver disease and kidney disease
Factors such as solubility, bioavailability, biological half-life, route of administration, product shelf life, as well as other pharmacological considerations are contemplated herein and the preparation of such pharmaceutical formulations or compositions is presented herein
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