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Results showed a fourfold higher risk for lung cancer among those who vaped and smoked cigarettes (OR = 38.7) compared with those who only smoked cigarettes (OR = 9.6)

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This chapter also investigates various mechanisms of toxicity from the perspectives of pulmonary, inflammation, oxidative stress, DNA damage, apoptosis, transcriptome alterations, and epithelial-mesenchymal transition (EMT), all of which are directly linked to the effects of e-cigs

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