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60 The Appellate Body noted, therefore, that substitutability did not have to exist throughout the market in order for products to be like

Six other studies that examined similar comparisons (sample size 80837) reported on smoking cessation and reduction but were all of very low certainty.29 35 One RCT that compared nicotine e-cigarettes to NRT ( n = 135) suggested there may be a large effect of e-cigarettes on cessation (161 more per 1000, 95% CI 15 more to 785 more

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13%) as well as young adults (11% vs

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