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Funding This work was supported by the Zhejiang Medical Association Clinical Medical Research Special Fund Project (No

doi:10.1155/2016/3286365 34

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Fouad K, Pedersen V, Schwab ME, Brsamle C

The Nrf2 activation along with the thiamine formation may explain why high doses of the thiamine disulfides, expected to decrease cellular redox potential, do not have any negative action even upon the long-term administration (155)