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Liver-type glutaminase GLS2 is a druggable metabolic node in luminal-subtype breast cancer

Distinct from apoptosis, necrosis and autophagy, Dixon and coauthors proposed for the first time a new form of oxidation-dependent and iron-dependent cell death known as ferroptosis [19]

High SAH levels particularly affect DNA methyltransferases, impacting the methylation status of certain genes, including the hTERT gene, which has implications for kidney function [60]

Mitochondrial activity in such cells is inseparable from its interactions with other intracellular compartments, including the endoplasmic reticulum (ER), lysosomes, the cytoskeleton, the plasma membrane, the nucleus, lipid droplets, peroxisomes, and secretory granules (6)

Turkderm 2014;48:2047

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