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The outcome was partially successfulthe tumor regressedbut the patient ultimately died from uncontrolled infection [32]

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Full optimization typically occurs by month 3-6 with ongoing monitoring and dosing adjustments

This result was also supported by insignificant improvements in serum AST and ALT levels (Fig

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Scramble 5UTR PRKAA1 -2: CTCACGGTGACGCCCTGCCGGGGCCCCCCCGCCTGCCCGCCCCCCTCCGGCTGGCGCTCGGCCTGCCGGTACTGCCGCGTCCCGGCCAGCCCGCGCCGCGCGGCCCCGCTTCCTCCCCCGGTCGAGGCGAGGGCCCCTAGCCCGGGCCGGCCCTCCCTCGCGTGTACCATCGGGCGCCACCGGCG