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It has done its job, but it is now sitting in an oxidized, used-up state and cannot do that job again until something restores it

104 Clinically, it is well established that weight loss and physical activity can reduce insulin levels by 1030%, and that lowering of insulin by 25% may be associated with a 5% absolute improvement in breast cancer mortality

Blood 88(10):67a, 1996

Most online discussions mention different approaches, but there is no universal standard

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