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Spinocerebellar ataxia: relationship between phenotype and genotype a review
For eight SRAs, SFB lineage designation was based solely on phylogenetic positioning due to equal nucleotide identity to more than one reference SFB 16S rRNA gene sequence (Supplementary Data 10)
Based on these limitations, we propose that future research should focus on the following specific directions: clarifying the upstream regulation mechanism, developing more complex experimental models, and promoting the transformation of clinical to precision medicine
However, additional research is required to clarify the mechanisms by which it works, enhance its bioavailability, and evaluate its long-term safety for broad use
doi: 10.1089/ars.2021.0204
Selenium deficiency impaired bone and cartilage growth with the exhibition of premature chondrocyte hypertrophy as evidenced by an increased expression of COLX, compatible with the phenotypes in KBD cartilage 64
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