Combined triad-GSH metabolism model simulations: impact of quinone metabolism on glutathione homeostasis The model was used to investigate how single vs constant 50 M exposure of doxorubicin influenced blood and cytosolic GSH and cysteine (Cys) levels, over a 10-hour time-span, shown in Fig
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The above studies have verified the inhibitory effects of quercetin on Cd-induced oxidative stress and other toxic functions, and further studies have shown that the combined treatment with -tocopherol (AT) and quercetin provided more significant protection against Cd-induced oxidative stress and lipid metabolism compared with quercetin alone, thereby reducing Cd-induced cardiovascular disease [128]
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