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Vitamin B12 supplements can be taken on an empty stomach, as long as you make sure you can handle it

Pycock JF, Allen WE: Inflammatory components in uterine fluid from mares with experimentally induced bacterial endometritis

This timing rationale is also discussed in relation to dosing frequency and peptide clearance in BPC-157 TB-500 Half-Life: Why Daily Dosing Beats Weekly

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No significant differences between the two groups in age (81.0 vs 82.0 years, P = 0.452), baseline NIHSS (median, 20.0 vs 22.0, P = 0.063), and ASPECTS (4.0 [3.05.0] vs 3.0 [2.04.75], P = 0.087)