An early multicenter, randomized, placebo-controlled study in individuals with AD of moderate severity found that supplementation with 2,000 IU/day of all - rac --tocopherol (equivalent to 900 mg/day of RRR --tocopherol) for two years significantly delayed cognitive decline, slowed disease progression, and increased median survival (107)
Jimnez-Arias D, Garca-Machado FJ, Morales-Sierra S et al (2019) Lettuce plants treated with L-pyroglutamic acid increase yield under water deficit stress
The research literature describes meaningful biological actions related to repair, inflammation regulation, and gene expression signaling, with ongoing interest in skin and connective tissue applications
Int J Food Microbiol 81(1):110
All claims reflect structure/function language based on human clinical data
The histomorphological changes in hepatotoxic liver enlargement without enzyme induction include fluid accumulation, fatty change in hepatocytes, inflammatory cell infiltration, fibrosis, and possibly granuloma formation (Glaister 1986