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(PMC2813286) studied TB-500 in murine models of Duchenne muscular dystrophy (DMD) in 2010

In heart failure

Animal findings frequently fail to translate directly into human medicine

TB500 is investigated for its association with actin polymerization dynamics and intracellular actin sequestration, which directly influences cell motility, differentiation, and structural reorganization

At the same concentration of 580 M, Cu(OAc) 2 induced a higher upregulation of IL1A than CuCl 2 , while CuCl 2 induced a higher upregulation of IL8, HSPA1A and FOSL1 than Cu(OAc) 2