IFN- and the IFN-+NAC combination presented an antiproliferative effect on 12Z cells
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Reactivated microglia showed enrichment for the thyroid hormone signaling pathway, including a putative enhancer for HIF-1 (Wendeln et al., 2018)
In addition, the treatment of nicotinamide (NAM), a form of vitamin B3, suppressed the activity of sirtuin-1 (SIRT1), a regulator of cellular stress resistance, and peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1), a key transcriptional coactivator involved in mitochondrial biogenesis and energy metabolism
However, as the only Cys residues present in Go-C3N-Nt 7 lay within the GFP sequence (Cys48 and Cys70), these results indicate that the remaining level of S-palmitoylation observed in these Nt 7 constructs originated from GFP
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