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Llavanera M, Delgado-Bermdez A, Fernandez-Fuertes B et al (2019) GSTM3, but not IZUMO1, is a cryotolerance marker of boar sperm

In mammals, NO is an important signaling molecule that plays various roles in physiological and pathological processes (Gantner et al

456,457,458 The primary advantage of covalent conjugation is that the resulting product is a single compound with defined structural and stoichiometric characteristics, aligning with the ideal properties for drug design and in vivo application

There are two variations of the suggested mechanism depending on whether the first GSH molecule attacks the Grx(SSR) intermediate at the sulfur atom of the glutaredoxin 60 or the substrate 15,30

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& Mimic-Oka, J