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For competitive transplantation, 250 freshly sorted HSCs (CD45.2) were mixed with 5 10 5 CD45.1 B6.SJL competitor bone-marrow cells and retro-orbitally injected into lethally irradiated B6.SJL recipient mice

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This is pharmacologically significant because the CYP450 system is the most common site of drug interactions

Huang L, Yu YY, Kirschke CP, Gertz ER, Lloyd KK

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